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Advanced RGN-6 is a potent skin regenerating cream inspired by laser regeneration science, designed to visibly improve 6 signs of aging. This patented formula is powered by 6 synergistic actives for 6 dimensions of rejuvenation and helps address key aging signs of visible redness, uneven skin tone, wrinkles, firmness and smoothness, with results visible starting in just 1 week.
Advanced RGN-6 is developed to be used both as part of a daily skincare routine, and physician tested to complement aesthetic procedures for optimal anti-aging results. Advanced RGN-6 helps reduce downtime post-procedure, aiding the skin in appearing less rough, smoother and more hydrated. Physician tested with laser on all skin tones.
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Advanced RGN-6 Benefits

Advanced RGN-6 Product Details
Advanced RGN-6 is a potent skin regenerating cream inspired by laser regeneration science, designed to visibly improve 6 signs of aging. This patented formula is powered by 6 synergistic actives for 6 dimensions of rejuvenation and helps address key aging signs of visible redness, uneven skin tone, wrinkles, firmness and smoothness, with results visible starting in just 1 week.
Advanced RGN-6 is developed to be used both as part of a daily skincare routine, and physician tested to complement aesthetic procedures for optimal anti-aging results. Advanced RGN-6 helps reduce downtime post-procedure, aiding the skin in appearing less rough, smoother and more hydrated. Physician tested with laser on all skin tones.
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The Science Behind Advanced RGN-6

Triggers 6 Dimensions of Rejuvenation
Advanced RGN-6 helps trigger 6 dimensions of skin rejuvenation to visibly improve signs of aging. Formulated with restorative ingredients like Glyco-Repair ™, eperuline, and niacinamide, this skin rejuvenation cream helps promote barrier renewal, reduce visible redness, and soothe discomfort. Ectoin, acetyl tetrapetide-9, and bioceramide 603 aid in visible rejuvenation by enhancing surface renewal, increasing elasticity, and reducing discoloration.

Inspired by Laser Regeneration Science
Laser treatments combat aging and uneven skin tone by creating controlled micro-damage that stimulates collagen production and skin regeneration. This process rejuvenates skin, resulting in a smoother, tighter, and brighter complexion. Advanced RGN-6 is inspired by laser regeneration science, formulated with 6 key actives for 6 distinct dimensions of skin rejuvenation.
Advanced RGN-6 is designed to be used daily for visibly rejuvenated skin, or post procedure to optimize anti-aging results and reduce downtime. Physician tested for use post laser procedure.

Developed With Nearly 20 Skin Regeneration Experts
Advanced RGN-6 was developed in collaboration with nearly 20 scientists specializing in skin regeneration. Over 5 years of extensive research, 1000+ data points were generated to support the performance of its core engine of 6 ingredients on repair and visible rejuvenation. Advanced RGN-6's exclusive technology holds three patents to promote barrier repair, improve pigmentation, and reduce post-treatment redness.
Key Ingredients

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10% Glyco-Repair
Glyco-Repair™ is an ingredient derived from locust beans that stimulates the skin’s re-epithelialization process in the upper layers of the skin. Epidermal renewal regeneration is key to maintaining even skin tone. Using Glyco-Repair™ can help slow the signs of aging by retaining a youthful glow and reducing fine lines and wrinkles

Eperuline 1%
Eperuline is a potent ingredient derived from the bark of the eperua falcata Aubl tree. An anti-inflammatory ingredient with antioxidant properties, eperuline in skincare has been shown to visibly improve firmness and elasticity. This powerful active ingredient works by keeping the skin barrier hydrated while inhibiting the proteins that activate visible signs of redness.

2% Niacinamide
Also known as vitamin B3, niacinamide is a water-soluble vitamin found naturally in yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains. Topical application of niacinamide has been shown to strengthen the skin’s moisture barrier and reduce the appearance of discoloration and blotchiness.

3% Acetyl Tetrapeptide-9
A powerful signal peptide, acetyl tetra-peptide 9 helps support skins structure and integrity for firmer, more resilient skin.

0.2% Ectoin
Ectoin is a naturally derived amino acid derivative that has been studied for its ability to reduce visible signs of damage caused by UV rays. This antioxidant helps organisms survive in extreme conditions, such as deserts or salt lakes, by maintaining cell stability and protein levels. Ectoin in skincare has been shown to help protect skin from oxidative stress, thereby reducing visible signs of aging like fine lines or wrinkles.

0.2% Bioceramide 603
A patented, exclusive ceramide analog, bioceramide-603 is shown to target discoloration and post-treatment redness.
How to Use Advanced RGN-6

Prep + Dispense
Once or twice daily after cleansing, apply 1-2 pumps of Advanced RGN-6 to face and neck.
Apply + Complete
Blend the product into the skin. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen.
Frequently Asked Questions
Advanced RGN-6 is a skin regenerative cream that helps trigger 6 dimensions of repair and can help improve signs of visible aging and skin tone.
No, Advanced RGN-6 is developed for both daily and post-procedure use. When used daily without procedure, it helps visibly reverse 6 signs of aging and skin tone damage starting in just 1 week.
Yes, Advanced RGN-6 can be used daily to visibly rejuvenate skin and improve the appearance of daily damage and aging.
Yes, retinol is a powerful combination with skin rejuvenation creams such as Advanced RGN-6. If using with a retinol at night, apply Advanced RGN-6 after retinol application.
Yes, it is recommended to apply Advanced RGN-6 after application of any products with hyaluronic acid.
Yes, if using with vitamin C in the morning, apply Advanced RGN-6 after vitamin C application.
Advanced RGN-6 is a regenerative cream that can be used immediately post-treatment to help soothe skin and improve laser outcomes. Following your treatment, apply Advanced RGN-6 in the morning and the evening after SkinCeuticals C E Ferulic®. For an added layer of protection, follow up Advanced RGN-6 with SkinCeuticals Epidermal Repair and Sheer Physical UV Defense SPF 50.
Free of added colorants, Advanced Regen-6 is naturally a shade of light taupe due to the presence of Ectoin. Please note that this color should be expected and does not affect the performance of the formula.